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br g Department of Pathology Ayub Medical College
2022-04-29
g Department of Pathology, Ayub Medical College, Abbottabad, Pakistan Keywords: Gastric cancer Palliative chemotherapy Cancer biomarkers CEA Background: Carcinoembryonic antigen (CEA), carbohydrate antigen (CA)-125, CA19-9, and CA72-4 are often found mod-ulated parameters in gast
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Loxapine Succinate br The other challenging problems of breast
2022-04-28
The other challenging problems of breast cancer histopathology image analyses are related to the limited number of available training samples and the imbalanced data problem. First, DCNNs are only effective when the number of available training samples is large enough during a training stage. Conv
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br Conflicts of interest The authors disclose no conflicts
2022-04-28
Conflicts of interest The authors disclose no conflicts. Funding This work was supported by the MD Anderson Moonshot Program and the Khalifa Bin Zayed Al-Nahyan Foundation (no grant numbers apply); the National Institutes of Health (U01CA196403 and U01CA200468 to Anirban Maitra); the Cancer
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3X FLAG Peptide br Center for Cancer Immunology and Cutaneous Biology
2022-04-27
1Center for Cancer Immunology and Cutaneous Biology Research Center, Department of Dermatology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA; 2Department of Pathology, Massachusetts General Hospital and Harvard Medical School,
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br Introduction br Cervical cancer CeCa represents a
2022-04-24
1. Introduction Cervical cancer (CeCa) represents a major public health problem worldwide, as more than 500,000 new cases and more than 250,000 deaths are detected each year, of which over 80% occur in developing countries [1]. Infection with high-risk human papillomavirus (HR-HPV) is considere
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br Schrader et al demonstrated that
2022-04-22
Schrader et al. [52] demonstrated that vimentin expression was upregulated with increasing stiffness of substrate. So far, the in-duction of EMT is believed to promote tumor cell motility and in-vasion. In another study, Tsuji et al. [53] reported collective migration for the role of EMT in cancer
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Cancer Letters br Sphere formation assay br Sphere culture was
2022-04-22
Cancer Letters 453 (2019) 158–169 2.4. Sphere formation assay Sphere culture was performed as previously described [24,25]. Briefly, Amiloride HCL were plated in 24-well Ultra-Low Attachment Plates (Corning) with DMEM: F12 medium plus 2% B27 (Gibco) and 20 ng/ml bFGF (PeproTech). The cultur
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br The AKT pathway is
2022-04-21
The AKT pathway is also known to crosstalk with the Notch signaling system [4]. A phosphorylation-specific antibody array for the activation of AKT pathway (Cell Signaling Technology) showed less phosphorylation of various AKT-related molecules in the COMP-expressing Iberiotoxin compared to contro
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br seekers report not being adverse to inadvertently
2022-04-17
seekers report not being adverse to inadvertently "bumping" into cancer information but find the information low in importance to them [16]. Guarded/active avoiders bypass cancer information altogether as it 6-NBDG is considered too distressing [16]. To my knowledge, such delineated cancer i
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br NP mM Tris HCl pH containing
2022-04-17
1% NP-40, 50 mM Tris-HCl [pH 7.5]) containing 0.1 mM Na2VO3, 1 mM NaF, and protease inhibitors (Sigma). For immunoblotting, proteins from whole cell lysates were resolved by 10% or 12% SDS-poly-acrylamide gel electrophoresis (PAGE) and then transferred to ni-trocellulose membranes. Primary Talapor
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br Breast cancer subtype distribution among
2022-04-16
3.2. Breast cancer subtype distribution among BPE types Among all patients with marked BPE, triple negative subtypes were significantly higher (p = 0.0074). 3.3. Multivariate regression analysis Fig. 1. Subtracted THRIVE Galactose 1-phosphate enhanced MR image showing a Luminal B HER2- b
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br The participants overall knowledge of BC risk factors
2022-04-16
The participants’ overall knowledge of BC risk factors and warning signs was calculated as described in the methodology of this (±)-Baclofen study . Figure 2 shows significant differences in responses related to limited level of knowledge between knowledge of risk factors and knowledge of warni
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Gene br Oligonucleotide pull down assay br Pull
2022-04-16
Gene 711 (2019) 143952 2.7. Oligonucleotide pull down assay Pull down assay was performed by extracting nuclear protein from MCF-7 and MDA-MB-231 Tigecycline using nuclear extraction kit (Thermo Scientific, USA). 3 μg of biotinylated MMP-9 wild motif, MMP-9 mutant motif and 300 μg of nuclea
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Chloramphenicol br capture as many features as possible maki
2022-04-15
capture as many features as possible, making acquired data potentially less reliable or robust as a result. In contrast, the highly reproducible targeted LC-MS/MS method we presented in this study was observed to have a median CV value of 5.1%, producing metabolic markers pre-viously unreported. F
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br Fig Scanning electron microscopy images
2022-04-15
Fig. 5. Scanning electron microscopy images of platelets in lysed whole blood (WB) samples co-incubated with T47D Liproxstatin-1 and its corresponding treatments. A: Platelet exposed to diluent-treated T47D cells displaying a smooth membrane with extending filipodia. B: Platelet exposed to media-
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